Iron deposition in apoferritin. Evidence for the formation of a mixed valence binuclear iron complex.

Initial iron oxidation in horse spleen apoferritin. Characterization of a mixed-valence iron(II)-iron(III) complex.

In ferritin, iron is stored by oxidative deposition of the ferrous ion to form a hydrous ferric oxide mineral core. Two intermediates, formed during the initial stages of iron accumulation in apoferritin, have been observed previously in our laboratory and have been identified as a mononuclear Fe3(+)-protein complex and a mixed-valence Fe2(+)-Fe3(+)-protein complex. The physical characteristics...

Double strand DNA cleavage with a binuclear iron complex.

Covalently linking two single strand DNA cleaving agents resulted in a new biomimetic binuclear iron complex capable of effecting oxidative double strand DNA cleavage.

R2 enhancement by formation of a tungsten-iron alloy crystal in the apoferritin cavity

V. Clavijo Jordan, and K. M. Bennett School of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ, United States Introduction: A fundamental challenge in molecular MRI is the sensitivity to delivered contrast agents (1). Thus, there is a critical need to increase the relaxivity of current contrast agents to detect sub-nanomolar concentrations in vivo. Natural nanopar...

Model Reactions for the Formation of Iron Deposition

Iron depositions, one of the non-transferrin-bound iron (NTBI), are frequently observed for the patients with hemochromatosis and several neurodegenerative disorders, such as Alzheimer’s and Parkinson’s diseases, etc. In this article, we have showed that iron deposition formation on the albumin proceeds in two different ways, one of them contains the participation of hydrogen peroxide, and the ...

Title Magnetic properties of mixed-valence iron phosphate glasses